Browsing by Author "Lourenzoni, Marcos Roberto"
Now showing items 1-16 of 16
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Analysis of the c-Myc tag presence in the CAR’s antigen-recognition domain structural stability, through molecular dynamics simulation
Lima, Ana Júlia Ferreira et al. | Date Issued: 2021 -
Anti-CD19 CAR-T engineering through Molecular Dynamics Simulation
Frota, Natália Fernandes et al. | Date Issued: 2019 -
Construction, by rational design, and initial characterization of affinity mutants of Rituximab fragment antibody
Pontes, Larissa Queiroz et al. | Date Issued: 2019 -
Development and optimization of the heterologous expression of a human L-asparaginase variant with potential enhanced catalytic activity
Guimarães, Ana Virgínia Frota et al. | Date Issued: 2021 -
Development of a biopharmaceutical derived from human L-asparaginase through in silico and in vitro evolution techniques
Guimarães, Ana Virgínia Frota et al. | Date Issued: 2024 -
Evaluation of the affinity between single-chain M971 antibody fragments and the CD22 membrane glycoprotein for a CAR-T Cell
Queiroz, Alice Soares de et al. | Date Issued: 2024 -
Human L-asparaginase engineering for improvement of catalytic activity and application in Acute Lymphoblastic Leukemia therapy
Pinheiro, Maisa Pessoa et al. | Date Issued: 2022 -
Interaction study of CD20 and Rituximab’s scFv to propose an anti-CD20 CAR
Rebouças, Alison de Sousa et al. | Date Issued: 2021 -
Modeling of the CD20 and CD52 membrane receptors and study of their interaction with DMPC membrane by molecular dynamic simulation
Lourenzoni, Marcos Roberto et al. | Date Issued: 2016 -
Production of a recombinant L-asparaginase and an immobilized biocatalyst to decrease the carcinogenic potential of French fries
Freitas, Lucas Almeida de et al. | Date Issued: 2024 -
Proposed mechanism for signal transduction of a CAR model in interaction with CD19, a cancer cell marker
Frota, Natália Fernandes et al. | Date Issued: 2021 -
Rational design of a human-like L-asparaginase as a strategy to improve catalytic efficiency
Pinheiro, Maísa Pessoa et al. | Date Issued: 2024 -
Reconversion of rituximab’s scFv into FvFc: a suitable format to understand CDR mutations of monoclonal antibodies
Bezerra, Marcus Rafael et al. | Date Issued: 2024 -
Study, by Molecular Dynamics simulation, of structural determinants of single-chain M971 antibody fragments for an anti-CD22 CAR-T cell
Queiroz, Alice Soares de et al. | Date Issued: 2023 -
The c-Myc-tag role in anti-CD19 scFv labeling and CAR’s function alteration: an in silico, in vitro and in vivo study
Lima, Ana Julia Ferreira et al. | Date Issued: 2022 -
Tool development for analysis of scFv NGS data in databases related to 3D structures: evolution of antibodies In silico
Batista, Mathias Coelho et al. | Date Issued: 2021